View Current Travel Advisories
Skip to Main Content
Trailways Home Page

Trailways Bus Tickets
from Birmingham, AL to Hannibal, MO

Choose one way or round trip:
(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for Hannibal, MO

Hannibal

Flag Stop, use arrow keys or tab to explore more about this bus station

Hannibal, MO 63401

Flag Stop
Address
4811 McMasters Avenue 
Hannibal, MO 63401
Phone Number
(319) 753-2864
More Detailsabout Hannibal Flag Stop

City InformationforBirmingham, AL

Prepare to be charmed as your bus to Birmingham, AL rolls into the “Magic City.” This Southern gem offers a delightful blend of history, culture, and irresistible local flavor that’ll make you want to take the scenic route. Start your adventure at the Civil Rights Institute, where history echoes in every corner and powerful stories come alive.

For an awe-inspiring view, head over to Vulcan Park - its iconic iron statue on Red Mountain is a sight to behold. And if a stroll through creativity is on your agenda, don’t miss the Birmingham Museum of Art, showcasing diverse collections ranging from Renaissance masterpieces to modern marvels.

Of course, you can’t leave town without sampling its renowned culinary delights. Try some authentic Southern BBQ at Saw’s and save room for the much-celebrated banana pudding.

When the sun goes down, the nightlife heats up in districts like Five Points South. Whatever your style, Birmingham is ready to welcome you with open arms and endless adventures. So, pack your bags and hop on that bus to Birmingham, AL - your next favorite destination awaits!

Scenic photo of Birmingham, ALScenic photo of Birmingham, ALScenic photo of Birmingham, AL
Scenic photo of Birmingham, AL
Scenic photo of Birmingham, AL
Scenic photo of Birmingham, AL

City InformationforHannibal, MO

Nestled on the banks of the mighty Mississippi, Hannibal, MO, is as charming as it is historical. Well-known as the boyhood home of Mark Twain, this delightful town takes you on a whimsical journey through American literature. Dive into the nostalgic world of the Mark Twain Boyhood Home & Museum, where the tales of Huck Finn come alive in the very spots that inspired them.

Whether you're exploring the depths of Mark Twain Cave or drifting leisurely along the river on a nostalgic riverboat cruise, you'll feel a world away from the ordinary. The town's friendly vibe extends to its quaint Main Street, where shops brim with local treasures and cafés invite lingering over a warm cup of coffee.

As you soak up the rich tapestry of stories that weave through this riverside gem, don’t forget to savor a scrumptious piece of homemade pie at a local diner, leaving you both satisfied and delighted. It’s time to secure a seat on your bus to Hannibal, where stories come to life, and every visit becomes a classic tale of adventure.

Frequently Asked Questions about the Bus Ride