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from Des Moines, IA to Saint Louis, MO

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Overview

About buses from Des Moines, IA to Saint Louis, MO

Buses from Des Moines, IA to Saint Louis, MO travel the 404mi (650.17km) journey, taking approximately 8h,. Usually, there is 1 bus operating per day including direct routes. While the average ticket price for this journey is around $117, you can find the cheapest bus tickets for as low as $117.

  • Distance
    404mi (650.17km)
  • Average bus duration
  • Average bus ticket price
    $117
  • Trips per day
    1
  • Direct routes
    1
  • Top Carriers
    Jefferson Lines

Bus Station Information for Saint Louis, MO

Saint Louis

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Saint Louis, MO 63102

24 Hours
Bus Station
Address
430 S. 15th Street 
Saint Louis, MO 63102
Phone Number
(314) 231-4485/(800) 858-8555
More Detailsabout Saint Louis Bus Station

Saint Louis (Airport - STL)

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Saint Louis, MO 63145

24 Hours
Advance Notice Required
Flag Stop
Address
10701 Lambert Intl Blvd 
Saint Louis, MO 63145
Phone Number
(319) 753-2864
More Detailsabout Saint Louis (Airport - STL) Flag Stop

City InformationforDes Moines, IA

All aboard for adventure in Des Moines, IA—a hidden gem in the heart of the Midwest that's sure to surprise and delight. Stepping off your bus to Des Moines, you'll find a town bustling with charm and brimming with activities. Start your exploration at the striking Pappajohn Sculpture Park, where art meets open air. Hungry? The lively East Village offers diverse dining that won't disappoint.

History buffs will enjoy a trip to the State Capitol, a masterpiece of 19th-century architecture with a golden dome that proudly shines over the city. Ready for some fun? Head to Adventureland Park, where thrilling rides await, or unwind in the serene beauty of the Greater Des Moines Botanical Garden.

Des Moines is also famous for its vibrant arts scene, with the Des Moines Art Center leading the charge. And don't forget the Saturday morning Downtown Farmers' Market, splendid any day of the week. Whether it’s art, architecture, or amusement parks, Des Moines serves up a hearty slice of Midwestern hospitality.

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City InformationforSaint Louis, MO

Welcome to Saint Louis, MO, a city that offers a diverse range of experiences bound to make every traveler feel right at home. Notably crowned by the iconic Gateway Arch, this urban gem is a perfect blend of historical charm and modern flair. Moving from sights to sound, immerse yourself in the musical legacy at the National Blues Museum or sway to a live jazz performance.

For animal lovers, the ever-popular Saint Louis Zoo offers free entry to a day filled with wonder and wildlife. Meanwhile, thrill-seekers might find the City Museum’s whimsical repurposed art exhibits both exhilarating and Instagram-worthy. And when it’s time to relax, grab a park bench in Forest Park and soak in its natural beauty.

No visit is complete without indulging in local eats – savor toasted ravioli or a gooey butter cake. Thriving with midwestern warmth and friendliness, this city promises an adventure that's both rich in culture and kind to the wallet. So why wait? Secure your seat on a bus to Saint Louis, and let the Gateway City open doors to new memories!

Frequently Asked Questions about the Bus Ride

Interested in bus routes from Des Moines to Saint Louis? You can take one of our 1 daily trips from Des Moines to Saint Louis for prices starting from $117.00. Schedule your bus trip to Saint Louis today!