View Current Travel Advisories
Skip to Main Content
Trailways Home Page

Trailways Bus Tickets
from Irvine, CA to San Diego, CA

Choose one way or round trip:
(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for San Diego, CA

San Diego

Bus Station, use arrow keys or tab to explore more about this bus station

San Diego, CA 92110

Bus Station
Address
4005 Taylor Street 
San Diego, CA 92110
Phone Number
(858) 800-8898
More Detailsabout San Diego Bus Station

San Diego (La Jolla - UC San Diego)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92093

Curbside Stop
Address
UCSD Health La Jolla Station 
San Diego, CA 92093
Phone Number
(858) 800-8898
More Detailsabout San Diego (La Jolla - UC San Diego) Curbside Stop

San Diego (Old Town)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92110

Curbside Stop
Address
2728 Congress St 
San Diego, CA 92110
Phone Number
(858) 800-8898
More Detailsabout San Diego (Old Town) Curbside Stop

San Diego (SDSU - Hardy Ave)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92115

Curbside Stop
Address
5716 Hardy Ave 
San Diego, CA 92115
Phone Number
(858) 800-8898
More Detailsabout San Diego (SDSU - Hardy Ave) Curbside Stop

City InformationforIrvine, CA

Pack your curiosity and hop on a bus to Irvine, CA, where adventure awaits beneath the Californian sun. This bustling town invites travelers like you to dive into its unique blend of nature, innovation, and culture. Irvine’s sprawling parks offer much more than a breath of fresh air. Venture onto the miles of scenic trails at Bommer Canyon or take an afternoon to unwind in the serene setting of Mason Regional Park.

But the city’s charms don’t stop at nature. The Irvine Spectrum Center is a vibrant hub for entertainment, shopping, and dining, featuring everything from thrilling rides on its iconic Giant Wheel to world-class dining that’ll satisfy any palate. The local vibe radiates a welcoming mix of tech-savvy innovation and laid-back SoCal spirit, a delightful setting for both heart-pumping and relaxing experiences.

Whether you’re gearing up for family fun, romantic escapes, or solo adventures, all roads lead to new memories in Irvine. Ready to roll? Book your bus to Irvine, CA, and let the journey be part of the adventure!

Scenic photo of {{ name }}
Scenic photo of {{ name }}
Scenic photo of {{ name }}

City InformationforSan Diego, CA

Pack your flip-flops and hop on a bus to San Diego, CA - where sunny skies and laid-back vibes effortlessly meet. Renowned for its stunning coastline and vibrant culture, San Diego offers budget-friendly adventures and unforgettable experiences. Start your journey in Balboa Park, with its lush gardens and impressive museums, perfect for a leisurely day of exploration.

Beach lovers will find paradise with miles of golden sands at popular spots like Mission Beach or the historic charm of Coronado Beach. Surfing, anyone? Don’t miss a chance to ride the waves at La Jolla Shores. If wildlife is your jam, the San Diego Zoo is world-class and not to be missed.

Dining here is a treat, from casual fish tacos by the shore to rooftop dining with views of that famous sunset. Stroll through the hip neighborhoods of North Park and Gaslamp Quarter for local shops and unique eats. Whatever draws you here, the chill pace of life ensures there's always time for one more adventure. Get started today with a bus to San Diego, CA, and soak in everything this coastal gem offers!

Frequently Asked Questions about the Bus Ride