View Current Travel Advisories
Skip to Main Content
Trailways Home Page

Trailways Bus Tickets
from Myrtle Beach, SC to Buffalo, NY

Choose one way or round trip:
(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Myrtle Beach, SC to Buffalo, NY

Buses from Myrtle Beach, SC to Buffalo, NY travel the 0mi (0.00km) journey, taking approximately 1d, 3h, 32m. Usually, there are 2 buses operating per day. While the average ticket price for this journey is around $276.95, you can find the cheapest bus tickets for as low as $257.46.

  • Average bus duration
  • Average bus ticket price
    $276.95
  • Trips per day
    2
  • Top Carriers
    Greyhound Lines

Bus Station Information for Buffalo, NY

Buffalo

Bus Station, use arrow keys or tab to explore more about this bus station

Buffalo, NY 14203

Trailways Bus Station
Address
181 Ellicott St 
Buffalo, NY 14203
Phone Number
(800) 858-8555
More Detailsabout Buffalo Bus Station

Buffalo (Airport - BUF)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Buffalo, NY 14225

24 Hours
Trailways Curbside Stop
Address
4200 Genesee St. 
Buffalo, NY 14225
Phone Number
(800) 858-8555
More Detailsabout Buffalo (Airport - BUF) Curbside Stop

City InformationforMyrtle Beach, SC

Let Myrtle Beach, SC, add a splash of adventure to your itinerary without splashing out! Whether you're a beach bum or a thrill-seeker, this coastal gem has got something for everyone. Start your day with a sunrise stroll along its sprawling sandy shores, perfect for finding those elusive, picture-perfect seashells. For thrill enthusiasts, Broadway at the Beach offers a fun-filled day of shopping, dining, and entertainment with attractions like Ripley’s Aquarium and live shows. Nature lovers can head to Myrtle Beach State Park for a relaxing hike or a picnic amid stunning ocean views. Meanwhile, golf lovers won't want to miss one of the area’s famed mini-golf courses.

Feeling hungry? Local seafood shacks serve up fresh, delectable catch-of-the-day specials that turn every meal into a coastal feast. And for those looking to experience history, the Hopsewee Plantation offers a glimpse into the past.

Planning your trip? Book a bus to Myrtle Beach and soak up all the sun-soaked memories this vibrant town has to offer. Adventure waits beyond every sand dune!

City InformationforBuffalo, NY

Look out, Buffalo, NY: your bus to Buffalo is about to deliver you to a city full of surprises. Nestled by the iconic Niagara Falls, this lively town packs a punch with a mix of culture, dining, and that special Buffalo vibe. It's a haven for art enthusiasts – make sure to check out the Albright-Knox Art Gallery with its mighty collection of modern masterpieces. For architecture buffs, Frank Lloyd Wright’s Darwin D. Martin House is a must-see.

Feeling peckish? Buffalo’s got you covered with its legendary wings. A stop at a local staple like Anchor Bar or Duff’s is practically a rite of passage. Beer aficionados will appreciate the craft breweries that have popped up all throughout the town – perfect for those looking to sample local flavors.

Nature lovers, don't miss a stroll through the tranquil Buffalo and Erie County Botanical Gardens. Whether you’re hitting the town solo or with friends, Buffalo’s rich history and welcoming energy promise plenty to keep you exploring. Get on that bus to Buffalo, NY, and discover a gem of a destination where every corner has a story to tell!

Scenic photo of Buffalo, NYScenic photo of Buffalo, NYScenic photo of Buffalo, NY
Scenic photo of Buffalo, NY
Scenic photo of Buffalo, NY
Scenic photo of Buffalo, NY

Frequently Asked Questions about the Bus Ride

Need information on buses from Myrtle Beach to Buffalo? If you want a fast and cheap way to get to Buffalo, or need an alternative to rail or airfare, Trailways helps you get there. Get your bus ticket to Buffalo now!