View Current Travel Advisories
Skip to Main Content
Trailways Home Page

Trailways Bus Tickets
from Philadelphia, PA to Florence, SC

Choose one way or round trip:
(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Philadelphia, PA to Florence, SC

Buses from Philadelphia, PA to Florence, SC travel the 0mi (0.00km) journey, taking approximately 17h, 51m. Usually, there are 18 buses operating per day. While the average ticket price for this journey is around $131.22, you can find the cheapest bus tickets for as low as $114.97.

  • Average bus duration
  • Average bus ticket price
    $131.22
  • Trips per day
    18
  • Top Carriers
    Greyhound Lines, FlixBus

Bus Station Information for Florence, SC

Florence

Bus Station, use arrow keys or tab to explore more about this bus station

Florence, SC 29501

Bus Station
Address
611 South Irby Street 
Florence, SC 29501
Phone Number
(800) 858-8555
More Detailsabout Florence Bus Station

Florence (TA Travel Center)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Florence, SC 29501

24 Hours
Curbside Stop
Address
2301 W. Lucas St 
Florence, SC 29501
Phone Number
(858) 800-8898
More Detailsabout Florence (TA Travel Center) Curbside Stop

City InformationforPhiladelphia, PA

Welcome to the City of Brotherly Love, also known as the birthplace of America and an epicenter of U.S. history. It's home to many historic sites, countless stories and cultural tales, and whether you’re a history buff, sports fan, film fanatic, or a foodie, Philly’s got something for you. So let freedom ring – from the Liberty Bell to your favorite Always Sunny spots.

If it’s your first visit, don’t skip the history: we’re talking Independence Hall, the Museum of the American Revolution, Betsy Ross House, the list goes on… And no matter how you decide to spend your day, make sure you work up an appetite before you book your bus tickets to Philadelphia. Those cheesesteak wars rage on, and you need to put on your battle gear.

Only one thing remains to be decided – with Whiz or without?

Scenic photo of {{ name }}
Scenic photo of {{ name }}
Scenic photo of {{ name }}

City InformationforFlorence, SC

All aboard for a delightful journey to Florence, SC, a charming town with Southern hospitality at its core. When your bus to Florence rolls in, get ready for a blend of culture, history, and good old-fashioned fun. Art lovers, kick off your adventure at the Florence County Museum and immerse yourself in regional history and breathtaking exhibits.

Craving outdoor activities? Hop on over to the Florence Rail Trail for a leisurely bike ride or a scenic walk amidst nature. If you fancy a bit of retail therapy, the Magnolia Mall will scratch that itch with a mix of national brands and local treasures. And speaking of local vibes, explore the downtown area with its quaint shops and lively arts scene.

Hungry after all that exploring? Florence has some delicious Southern cuisine options waiting to tantalize your taste buds. Before you hit the road, don't forget to snap a pic at the iconic Florence Veterans Park. With so much to discover, your ticket to Florence, SC, promises an adventure filled with laughs, local charm, and memories you'll cherish for years to come.

Frequently Asked Questions about the Bus Ride

Planning on taking the bus from Philadelphia to Florence? There are 18 trip(s) leaving Philadelphia and arriving in Florence about 17 hour(s) 51 minute(s) later every day. Get your bus ticket to Florence now!