View Current Travel Advisories

Trailways Bus Tickets
from Frederick, MD to Sioux Falls, SD

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Frederick, MD to Sioux Falls, SD

Buses from Frederick, MD to Sioux Falls, SD travel the 1040mi (1673.71km) journey, taking approximately 1d, 11h, 10m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $237.33, you can find the cheapest bus tickets for as low as $237.33.

  • Distance
    1040mi (1673.71km)
  • Average trip duration
  • Average bus ticket price
    $237.33
  • Trips per day
    1
  • Top Carriers
    Greyhound Lines

Bus Station Information for Sioux Falls, SD

Sioux Falls (Maple Mall)

Bus Station, use arrow keys or tab to explore more about this bus station

Sioux Falls, SD 57107

Bus Station
Address
4110 West Maple St. Suite 108
Sioux Falls, SD 57107
Phone Number
(605) 336-0885/(858) 800-8898/(800) 858-8555
More Detailsabout Sioux Falls (Maple Mall) Bus Station

City InformationforFrederick, MD

Looking for a delightful escape that balances history, nature, and culinary delights? Your bus to Frederick, MD is ready to whisk you away to this charming town. Nestled in the heart of Maryland, Frederick offers a scenic blend of cobblestone streets and rolling landscapes. History buffs will absolutely adore the National Museum of Civil War Medicine, a unique stop that sheds light on fascinating 19th-century medical practices. Meanwhile, art lovers can rejoice at the vibrant offerings of the Delaplaine Arts Center.

Catch a breath of fresh air with a visit to the Great Frederick Fairgrounds or crisscross your way through picturesque Carroll Creek Park. Whispered among locals are tales of ghost tours, adding an element of intrigue to your visit. As the sun dips, meander through the streets sparkling with local eateries. Frederick’s spirited dining scene boasts everything from crabcakes to farm-fresh twists, promising palates a feast of flavor.

Seize the opportunity to create lasting memories. Book your bus tickets to Frederick, MD and let the adventure unfold!

City InformationforSioux Falls, SD

Sioux Falls, SD might not be on your radar yet, but once you hop on a bus to Sioux Falls, you'll find a destination with charm to spare. This friendly town is home to stunning natural beauty, buzzing cultural scenes, and enough unique local flavor to keep any traveler entertained. Nature lovers will find themselves drawn to Falls Park, where the picturesque Big Sioux River cascades down glittering tiered rocks, a perfect spot for strolling or snapping a few Instagram-worthy pics. If you're in the mood for art, the SculptureWalk brings Sioux Falls' downtown streets alive with dozens of dynamic sculptures.

What really seals the deal? The city’s bustling downtown offers an array of unique dining experiences and cozy coffee spots where you can unwind like a local. Plus, with street festivals, local music, and that welcoming Midwestern warmth, you're set for a memorable visit. So, when the urge to explore strikes, just grab your bus tickets to Sioux Falls, and let the adventure begin!

Frequently Asked Questions about the Bus Ride

Interested in bus routes from Frederick to Sioux Falls? Trailways has 1 Sioux Falls-Frederick trips starting at $237.33. Get your bus ticket to Sioux Falls today!