View Current Travel Advisories

Trailways Bus Tickets
from Greenville, SC to Panama City, FL

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Greenville, SC to Panama City, FL

Buses from Greenville, SC to Panama City, FL travel the 379mi (609.94km) journey, taking approximately 17h, 15m. Usually, there are 2 buses operating per day. While the average ticket price for this journey is around $170.97, you can find the cheapest bus tickets for as low as $152.96.

  • Distance
    379mi (609.94km)
  • Average trip duration
  • Average bus ticket price
    $170.97
  • Trips per day
    2
  • Top Carriers
    Greyhound Lines, FlixBus

Bus Station Information for Panama City, FL

Panama City

Bus Station, use arrow keys or tab to explore more about this bus station

Panama City, FL 32407

Bus Station
Address
7808 Panama City Beach Pkwy. 
Panama City, FL 32407
Phone Number
(800) 858-8555
More Detailsabout Panama City Bus Station

City InformationforGreenville, SC

Pack your bags and get ready to fall for Greenville, SC - a town bursting with Southern charm and surprises. Hop on a bus to Greenville, SC, and discover all this gem has to offer. Start your journey by wandering through Falls Park on the Reedy, where gentle waterfalls and lush gardens provide the perfect setting for a picnic or a peaceful stroll. If you’re an art enthusiast, the Greenville County Museum of Art awaits with a stunning collection, while the local galleries dotting the area are sure to catch your eye.

Looking for adventure with a side of nature? The Swamp Rabbit Trail offers a scenic route for biking or walking, weaving through the town's vibrant neighborhoods. Make sure to swing by the Greenville Zoo for a family-friendly outing with creatures from around the globe.

Greenville’s food scene is buzzing. From quaint cafes to upscale eateries, your taste buds are in for a treat. With its blend of culture, cuisine, and charming green spaces, Greenville, SC, is calling your name. Book that bus ticket, and let the adventure begin!

City InformationforPanama City, FL

Welcome to Panama City, FL, where effortless southern charm meets sandy beach vibes. This fun-filled town is famous for its sugar-white sands and turquoise waters that stretch as far as the eye can see. Whether you're in the mood for a laid-back beach day or an adventure, you've come to the right place. Dive into the stunning marine world at Gulf World Marine Park or explore the great outdoors at St. Andrews State Park, a haven for snorkelers and hikers alike.

If you lean more toward city pleasures, a stroll through the quaint shops and eateries of historic St. Andrews will immerse you in local flavor. And when your hunger strikes, indulge in some fresh seafood; the Gulf’s bounty never disappoints! With friendly locals and laid-back activities, Panama City exudes chill vibes perfect for a refreshing escape.

Ready to make memories in this Gulf Coast gem? Secure your spot on a bus to Panama City, and see what makes this town a true southern treasure.

Frequently Asked Questions about the Bus Ride

Want to know more about taking the bus from Greenville to Panama City? Trailways gives you the cheap, fast fares you need when you're traveling. Comfort, convenience, and affordability. Buy your Panama City bus ticket today.