View Current Travel Advisories

Trailways Bus Tickets
from Ithaca, NY to Big Pine Key, FL

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Ithaca, NY to Big Pine Key, FL

Buses from Ithaca, NY to Big Pine Key, FL travel the 1259mi (2026.16km) journey, taking approximately 1d, 23h, 40m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $331.45, you can find the cheapest bus tickets for as low as $331.45.

  • Distance
    1259mi (2026.16km)
  • Average trip duration
  • Average bus ticket price
    $331.45
  • Trips per day
    1
  • Top Carriers
    FlixBus

Bus Station Information for Big Pine Key, FL

Big Pine Key

Curbside Stop, use arrow keys or tab to explore more about this bus station

Big Pine Key, FL 33043

Curbside Stop
Address
29975 Overseas Hwy 
Big Pine Key, FL 33043
Phone Number
(800) 858-8555
More Detailsabout Big Pine Key Curbside Stop

City InformationforIthaca, NY

Welcome to Ithaca, NY, a town that marries natural beauty with a quirky, intellectual charm. If you're seeking an escape into the heart of Finger Lakes, look no further. A bus to Ithaca can whisk you away to a place where stunning waterfalls and vibrant city life coexist seamlessly. Kickstart your adventure with a visit to Ithaca Falls or explore the rugged beauty of the gorges at Buttermilk Falls State Park. Both offer Instagram-worthy views that will make your friends green with envy. Once you've had your fill of nature, take a stroll through the Ithaca Commons—a pedestrian paradise home to eclectic shops and street performers that bring the area to life.

For a taste of Ithaca's intellectual vibe, swing by the Cornell Botanic Gardens or catch a lecture at Cornell University. But let’s not forget the local cuisine; sample something fresh from Moosewood Restaurant, known for its pioneering vegetarian dishes. Overall, whether you're in it for the landscapes or the lively local culture, Ithaca offers a soul-refreshing experience that's just a bus ride away.

Scenic photo of Ithaca, NYScenic photo of Ithaca, NYScenic photo of Ithaca, NY
Scenic photo of Ithaca, NY
Scenic photo of Ithaca, NY
Scenic photo of Ithaca, NY

City InformationforBig Pine Key, FL

Take a bus to Big Pine Key, FL, and immerse yourself in the idyllic heart of the Florida Keys. This laid-back town is a slice of paradise where natural beauty and relaxation collide. Known for its stunning landscapes and famous Key deer, the town offers a unique charm that’ll leave you longing for more.

Kick off your adventure with a visit to the National Key Deer Refuge, where you can watch these gentle creatures roam freely. For water enthusiasts, the crystal-clear waters beckon for kayaking or snorkeling trips in the nearby Looe Key Reef. Sun-seekers will love the sandy stretches of Bahia Honda State Park, perfect for unwinding under the swaying palms.

Beyond nature, Big Pine Key serves up a delightful local flair with its quirky shops and eateries. Catch a sunset and maybe even a live music performance at one of the waterfront spots that locals love.

Why wait any longer? Your blissful island escape awaits, so grab your bus tickets to Big Pine Key and let the adventure begin!

Frequently Asked Questions about the Bus Ride

Are you taking the bus from Ithaca to Big Pine Key? Trailways has 1 Big Pine Key-Ithaca trips starting at $331.45. Get to Big Pine Key affordably. Buy your bus ticket online.