View Current Travel Advisories

Trailways Bus Tickets
from Portland, ME to Key West, FL

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Portland, ME to Key West, FL

Buses from Portland, ME to Key West, FL travel the 1472mi (2368.95km) journey, taking approximately 2d, 9h, 31m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $236.44, you can find the cheapest bus tickets for as low as $236.44.

  • Distance
    1472mi (2368.95km)
  • Average trip duration
  • Average bus ticket price
    $236.44
  • Trips per day
    1
  • Top Carriers
    FlixBus

Bus Station Information for Key West, FL

Key West

Bus Station, use arrow keys or tab to explore more about this bus station

Key West, FL 33040

Bus Station
Address
3439 S. Roosevelt Blvd. 
Key West, FL 33040
Phone Number
(800) 858-8555
More Detailsabout Key West Bus Station

Key West (FlixBus)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Key West, FL 33040

Curbside Stop
Address
910 Caroline Street 
Key West, FL 33040
Phone Number
(800) 858-8555
More Detailsabout Key West (FlixBus) Curbside Stop

City InformationforPortland, ME

Ready for a coastal escape without breaking the bank? Book your bus to Portland, ME, and dive into a charming town that blends maritime heritage with modern flair. Portland boasts a vibrant arts and culture scene, delectable dining options, and picturesque scenery. Start with a leisurely wander through the historic Old Port district, where cobblestone streets lead you to unique boutiques and craft breweries.

If you're seeking a splash of nature, the Eastern Promenade offers stunning waterfront views and trails perfect for a brisk walk or a casual bike ride. Don’t skip the Portland Museum of Art, where you’ll find an impressive collection ranging from local masterpieces to international works. For seafood lovers, the town’s renowned lobster rolls are a must-try - where fresh catches are the star on every menu.

With so much culture, cuisine, and coastline to explore, Portland awaits with its unique blend of small-town charm and lively spirit. Hop on a bus to Portland, ME, and get ready to create unforgettable memories!

City InformationforKey West, FL

Step aboard a bus to Key West, FL, where the laid-back island life meets vibrant culture and history! As you cruise along the Overseas Highway, prepare to be enchanted by this colorful town. Key West isn’t just sunshine and sandy beaches, though we’ve got plenty of that. It’s also home to literary legend Ernest Hemingway’s house, where roaming six-toed cats keep things interesting.

Feeling adventurous? A snorkeling tour through the coral reefs at Dry Tortugas National Park is a must. For a touch of history, Fort Zachary Taylor’s Civil War heritage and lush surroundings offer a unique blend of learning and leisure. When hunger strikes, dig into some conch fritters or savor more refined tastes at Duval Street’s eclectic mix of eateries.

With its lively art scene, whimsical architecture, and island sunsets that are pure magic, this town invites you to kick back and relax. Hop on a bus to Key West, FL, and let the adventures begin. Your island escapade awaits!

Frequently Asked Questions about the Bus Ride

Reach Key West easily by bus from Portland. We have daily departures from Portland to Key West starting as low as $236.44. Find the best bus tickets for you from Portland to Key West.