View Current Travel Advisories

Trailways Bus Tickets
from Portsmouth, OH to San Francisco, CA

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Portsmouth, OH to San Francisco, CA

Buses from Portsmouth, OH to San Francisco, CA travel the 2125mi (3419.85km) journey, taking approximately 3d, 13h, 25m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $373.49, you can find the cheapest bus tickets for as low as $373.49.

  • Distance
    2125mi (3419.85km)
  • Average trip duration
  • Average bus ticket price
    $373.49
  • Trips per day
    1
  • Top Carriers
    Barons Bus Lines

Bus Station Information for San Francisco, CA

San Francisco

Bus Station, use arrow keys or tab to explore more about this bus station

San Francisco, CA 94105

Bus Station
Address
425 Mission St. 
San Francisco, CA 94105
Phone Number
(800) 858-8555
More Detailsabout San Francisco Bus Station

San Francisco (5th & Townsend)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Francisco, CA 94107

Curbside Stop
Address
409 Townsend Street 
San Francisco, CA 94107
Phone Number
(800) 858-8555
More Detailsabout San Francisco (5th & Townsend) Curbside Stop

San Francisco (Fisherman's Wharf)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Francisco, CA 94109

Curbside Stop
Address
700 Beach Street 
San Francisco, CA 94109
Phone Number
(800) 858-8555
More Detailsabout San Francisco (Fisherman's Wharf) Curbside Stop

San Francisco (Daly City BART)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Francisco, CA 94014

Curbside Stop
Address
500 John Daly Blvd 
San Francisco, CA 94014
Phone Number
(800) 858-8555
More Detailsabout San Francisco (Daly City BART) Curbside Stop

City InformationforPortsmouth, OH

Nestled along the scenic Ohio River, Portsmouth, OH offers a blend of rich history and serene landscapes that’s just one bus ride away. The town’s renowned Floodwall Murals stretch along the riverfront, painting a vivid picture of its vibrant past. For those craving outdoor adventure, Shawnee State Park offers enticing trails that beckon hikers and explorers alike with their unspoiled beauty.

Portsmouth isn't just about history and trails, it's also a town pulsing with unique local energy. Downtown is dotted with cafes and quirky shops, perfect for a leisurely afternoon stroll. Don’t miss the charming antique stores where treasures of the past meet the charm of the present, giving you a taste of the town’s eclectic spirit. If you’re into live entertainment, Southern Ohio’s music scene is alive and kicking, with performances that’ll have your toes tapping before you know it.

Eager for a getaway that combines cultural richness with small-town charisma? Start planning your adventure by booking a bus to Portsmouth, OH. This welcoming town is ready to reveal its stories and sights.

City InformationforSan Francisco, CA

When the fog rolls into San Francisco, CA, it's like a cozy invitation to savor a town bursting with iconic charm. Take your next adventure on a bus to San Francisco, and you'll find more delights than just the Golden Gate Bridge. Begin at Fisherman’s Wharf, where street performers add a whimsical touch, and sample world-class seafood. History enthusiasts will love wandering through the haunting walls of Alcatraz Island, while culture vultures can revel in the vast collections within the San Francisco Museum of Modern Art.

For a taste of the local vibe, hop on a cable car and ride through the quirky streets of Haight-Ashbury or explore the vibrant shops and eateries that make Chinatown sing with flavor. Green thumbs (and photographers) shouldn’t miss the Botanical Gardens in Golden Gate Park for a tranquil escape. Whether it’s the distinctive neighborhoods or the panoramic city views from Twin Peaks, every corner of San Francisco is ready to enchant you, especially when you roll into town with the reliable comfort of a Trailways bus.

Scenic photo of San Francisco, CAScenic photo of San Francisco, CAScenic photo of San Francisco, CA
Scenic photo of San Francisco, CA
Scenic photo of San Francisco, CA
Scenic photo of San Francisco, CA

Frequently Asked Questions about the Bus Ride

Make it easy to get from Portsmouth to San Francisco by taking a bus. Buses depart from Portsmouth to San Francisco 1 time per day. Prices start at $373.49. Find the best bus tickets for you from Portsmouth to San Francisco.